Tadalafil is prescribed for the treatment of erectile dysfunction or to treat male impotence. Tadalafil is phosphodiesterase type 5 inhibitor increase the blood flow during sexual stimulation, achieve and maintain an erection.
Tadalafil causes no considerable change in a healthy person in diastolic and systolic blood pressure as compared to placebo in the supine position and it also do not effect in heart rate. Tadalafil does not change the color recognition as it has been explained by its low affinity for FDE6. Moreover, there is no marked effect of tadalafil on intraocular or electroretinogram pressure.

Contraindications Of Tadalafil: As mentioned above, Tadalafil drug is designed to relieve the men from erectile or dysfunction impotency. However, if a person has decided to take the advantage of Tadalafil 20mg then he needs to know the correct usage of the tablets as directed by the physician. A lot of people fail to get the exact outcome of the Tadalafil because of the improper usage of the dose. Thus, it is important to follow the instructions as prescribed to get the best results to enhance the effects of Tadalafil.
An average person starts noticing the effects of tadalafil after 30 minutes of taking the pill. Before doing sexual activities one should that tadalafil an hour before. The effects of taking and following the instructions of how to take Tadalafil tablets last for at least three hours after taking the pill. However, Tadalafil should be taken was prescribed only. If you exceed the Tadalafil dosage as advised by the physician will ultimately result into bad experience and you will not get the desired results and you sexual stamina will also not improve. On the other hand, by taking the dose of Tadalafil more than it is intended will also result into unpleasant side effects on your system.

The Influence Of Other Drugs On Tadalafil: Tadalafil is essentially metabolized by the enzyme CYP3A4 participation. However, CYP3A4 inhibitor namely ketoconazole enhances the AUC by 107% while rifampicin drops it by 88%. In spite of the fact that the certain interactions have not been found out, it can be assumed that inhibitors such as saquinavir, ritonavir, itraconazole and erythromycin can increase the Tadalafil activity.
Also in take of any antacid such as magnesium hydroxide or aluminum hydroxide can reduce the absorption rate.

Do not use Tadalafil when:
- If you have already taken nitrates or mononitrate for chest pain as your blood pressure may suddenly get low.
- Drugs like amyl nitrite and butyl nitrite can cause reaction or cannot be healthy.
- If you are allergic or sensitive case for any of the ingredients of tadalafil, instantly call to your healthcare service and get help if you feel any symbol of allergic reaction like hives, rash, and swelling on throat or if you experience swallowing or breathing difficulty.

Possible Side Effects Of Tadalafil: Side effects of Tadalafil medicine are dizziness, headache, indigestion, and aches in muscles, stuffy nose etc. These side effects usually start appearing within few hours. Men usually feel muscle aches and back pain usually after 12 to 24 hours and these remain for 2 days.
However, there is no side effect of a single dose of Tadalafil on the absorption of ethanol in the blood and its influence on cognitive function and on blood pressure. It could be said that there is no change in the level of concentration by Tadalafil has clinically no significant effect on pharmacodynamics of theophylline. tadalafil in the blood after 3 hours of taking with ethanol combination.

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